Speare, D. J., et al. “Development of an Effective Whole-Spore Vaccine to Protect Against Microsporidial Gill Disease in Rainbow Trout (Oncorhynchus Mykiss) by Using a Low-Virulence Strain of Loma Salmonae”. Clinical and Vaccine Immunology, vol. 14, no. 12, 2007, pp. 1652-4, https://doi.org/10.1128/CVI.00365-07.

Genre

  • Journal Article
Contributors
Author: Speare, D. J.
Author: Guselle, N. J.
Author: Markham, R. J. F.
Date Issued
2007
Abstract

In determining the effective vaccine spore dose of a low-virulence strain of Loma salmonae to limit micro-sporidial gill disease in trout, we found that fish receiving 10(3) to 10(5) killed spores had the best protection against experimental infection, with 85% fewer xenomas in their gills than in the controls. Intraperitoneal delivery of the vaccine was effective, and the addition of adjuvant did not improve vaccine performance against this disease-causing microsporidian.

Note

[Speare, D. J.; Markham, R. J. F.; Guselle, N. J.] Univ Prince Edward Isl, Atlantic Vet Coll, Dept Pathol & Microbiol, Charlottetown, PE C1A 4P3, Canada.; Speare, DJ, Univ Prince Edward Isl, Atlantic Vet Coll, 550 Univ Ave, Charlottetown, PE C1A 4P3, Canada.; speare@upei.ca

WASHINGTON; 1752 N ST NW, WASHINGTON, DC 20036-2904 USA

AMER SOC MICROBIOLOGY

PT: J; NR: 16; TC: 3; J9: CLIN VACCINE IMMUNOL; PG: 3; GA: 242DM

Source type: Electronic(1)

Language

  • English

Subjects

  • aquaculture
  • RESISTANCE
  • Infectious diseases
  • Immunology
  • Microbiology
  • immunity
  • parasites
  • VARIANT
Page range
1652-1654
Host Title
Clinical and Vaccine Immunology
Host Abbreviated Title
Clin.Vaccine Immunol.
Volume
14
Issue
12
ISSN
1556-6811
DOI
https://doi.org/10.1128/CVI.00365-07

Department