SCHOLAR DETAILS
Name
Barry Linkletter
Email
blinkletter@upei.ca
Position
Faculty Member
Department(s)
Chemistry
Phone
902-628-4328
Building
Irving Chemistry Centre 205
Website
https://www.upei.ca/profile?u=blinkletter
Status
Current
Biography

Chair, Chemistry; Associate Professor

BSc (UPEI); PhD (McGill)

Dr. Barry Linkletter works to better understand and synthesize molecules that will interact and associate with four-stranded DNA, a novel DNA structure. These stabilizing molecules are candidates for drugs that regulate cell proliferation and may find a use in cancer therapy and genetic research.

Recent Citations
Solid-phase synthesis of deoxynucleic guanidine (DNG) oligomers and melting point and circular dichroism analysis of binding fidelity of octameric thymidyl oligomers with DNA oligomers
Journal of the American Chemical Society, 1999
Rapid hydrolysis of 2 ',3 '-cAMP with a Cu(II) complex: effect of intramolecular hydrogen bonding on the basicity and reactivity of a metal-bound hydroxide
Journal of the American Chemical Society, 1999
Synthesis of protected guanidinium linked dinucleoside incorporable into an oligonucleotide using solid phase DNA methodology
Bioorganic & Medicinal Chemistry Letters, 1998
Rapid hydrolysis of RNA with a CU-II complex
Angewandte Chemie-International Edition in English, 1995
Benzylchlorocarbene: UV absorption spectrum, kinetics for 1,2-H migration and mechanism for reaction with acetic acid as determined by combined continuous and laser-flash photolysis
Laser Chemistry, 1990
Research Interests
Molecular recognition of DNA secondary structures
Telomeric DNA
Solid-phase organic synthesis
Novel nucleotide bases