Olfactory neuron biopsies in dogs: A feasibility pilot study

Olfactory neurons obtained through nasal biopsy were characterized. Using standard immunohistochemical techniques, nascent, developing, and mature neurons were identified in the tissues obtained. This technique shows that aspects of canine olfactory function may be potentially assessed using a relatively simple and minimally invasive biopsy technique. Such samples provide direct access to neuronal tissue that is otherwise difficult to obtain and assess in living animals. This technique may have potential value to those interested in assessing olfactory abilities in dogs.