Gilmour, Robert F. “The Anatomy of an Arrhythmia”. Journal of Clinical Investigation, vol. 113, no. 5, 2004, pp. 662-4, https://doi.org/10.1172/jci21223.

Genre

  • Journal Article
Contributors
Author: Gilmour, Robert F.,,Jr
Date Issued
2004
Abstract

Computer simulations are potentially effective approaches to unraveling the causes of lethal heart rhythm disorders. In this issue of the JCI, Xie et al. have embedded a well-characterized dynamic mechanism for arrhythmia development in an anatomically realistic computer model of the heart. Their demonstration that this simple mechanism governs the behavior of the complex model may provide a new target for strategies to prevent sudden death.

Note

Department of Biomedical Sciences, Cornell University, Ithaca, New York 14853-6401, USA. rfg2@cornell.edu

United States

American Society for Clinical Investigation : Ann Arbor, MI

Accession Number: 14991062. Language: English. Language Code: eng. Date Revised: 20100920. Date Created: 20040301. Date Completed: 20040413. Update Code: 20111122. Publication Type: Comment; Journal Article. Journal ID: 7802877. Publication Model: Print. Cited Medium: Print. NLM ISO Abbr: J. Clin. Invest. PubMed Central ID: PMC351330. Cites: Physiol Rev. 1989 Oct;69(4):1049-169. (PMID: 2678165). Cites: Circulation. 1998 Nov 24;98(21):2334-51. (PMID: 9826323). Cites: Proc Natl Acad Sci U S A. 2000 May 23;97(11):6061-6. (PMID: 10811880). Cites: Circ Res. 2000 Nov 24;87(11):964-5. (PMID: 11090538). Cites: Science. 2002 Mar 1;295(5560):1678-82. (PMID: 11872832). Cites: Annu Rev Biomed Eng. 2003;5:147-77. (PMID: 14527312). Cites: J Appl Physiol. 1968 Aug;25(2):191-6. (PMID: 5666097). Cites: N Engl J Med. 1994 Jan 27;330(4):235-41. (PMID: 8272084). Cites: J Cardiovasc Electrophysiol. 1999 Aug;10(8):1087-9. (PMID: 10466489). Cites: Circulation. 2000 Oct 3;102(14):1664-70. (PMID: 11015345). Cites: J Cardiovasc Electrophysiol. 2001 Feb;12(2):196-206. (PMID: 11232619). Cites: Circ Res. 2002 Feb 22;90(3):289-96. (PMID: 11861417). Cites: J Clin Invest. 2004 Mar;113(5):686-93. (PMID: 14991066). Comment on: J Clin Invest. 2004 Mar;113(5):686-93. (PMID: 14991066). Linking ISSN: 00219738. Subset: AIM; IM. Date of Electronic Publication: 20040301; ID: 14991062

Language

  • English

Subjects

  • Humans
  • Ventricular Fibrillation
  • Arrhythmias, Cardiac/*pathology
  • Computer Simulation
  • Arrhythmias, Cardiac/*diagnosis
  • Models, Cardiovascular*
  • Heart/*anatomy & histology
Rights
Contact Publisher
Page range
662-664
Host Title
Journal of Clinical Investigation
Host Abbreviated Title
J.Clin.Invest.
Volume
113
Issue
5
ISSN
0021-9738
DOI
https://doi.org/10.1172/jci21223

Department