Markham, R. J. Frederick, et al. “Inhibition of Phagosome-Lysosome Fusion in Macrophages by Soluble Extracts of Virulent Brucella Abortus”. American Journal of Veterinary Research, vol. 46, no. 2, 1985, pp. 332-5, https://scholar2.islandarchives.ca/islandora/object/ir%3Air-batch6-3643.

Genre

  • Journal Article
Contributors
Author: Markham, R. J. Frederick
Author: Frenchick, P. J.
Author: Cochrane, A. H.
Date Issued
1985
Abstract

Water extracts of virulent Brucella abortus were able to inhibit phagosome-lysosome fusion in unelicited murine peritoneal macrophages following ingestion of yeast. Extracts from an avirulent strain were unable to produce a similar effect. Lipopolysaccharide from B abortus did not appear to be involved with the ability of the extracts to inhibit fusion.

Note

UNITED STATES

LR: 20061115; PUBM: Print; JID: 0375011; 0 (Lipopolysaccharides); ppublish

Source type: Electronic(1)

Language

  • English

Subjects

  • animals
  • Peritoneum/cytology
  • Mice
  • Lipopolysaccharides/pharmacology
  • Phagocytosis
  • Brucella abortus/pathogenicity
  • Body Fluids/physiology
  • Lysosomes/physiology
  • Virulence
  • Membrane Fusion/drug effects
  • Saccharomyces cerevisiae/physiology
  • Allantois
  • Macrophages/physiology
Page range
332-335
Host Title
American Journal of Veterinary Research
Host Abbreviated Title
Am.J.Vet.Res.
Volume
46
Issue
2
ISSN
0002-9645

Department