Genre
- Journal Article
Effect of Tower rapeseed oil (RO) containing lower (0.4%) erucic acid on the piglet liver was studied by electron microscopy. The animals were placed in two groups of four and were fed the diets for eight weeks. Animals in the treated group were given a basal diet comprising corn-soybean plus Tower RO at a 10% concentration; animals that were given the basal diet with no added oil served as the controls. Architecture of the liver from animals of the control group appeared normal. Ultrastructural changes in the liver of RO-fed animals included dilation of lumens and loss of microvilli in bile canaliculi. In addition, closely aligned mitochondrial cristae, elevated number of peroxisomes, and an unusual increase in the size and number of membrane bound spaces in zone 3 of liver acini were noticed. These alterations may reflect a disturbance in piglet liver functions following Tower RO feeding.
ATLANTIC VET COLL,DEPT ANAT & PHYSIOL,CHARLOTTETOWN,PE C1A 4P3,CANADA. ONTARIO VET COLL,GUELPH,ON,CANADA.
MURCIA; PLAZA FUENSANTA 2-7 C, 30008 MURCIA, SPAIN
F HERNANDEZ
PT: J; CR: ABDELLATIF AMM, 1970, STE ADELE QUEBE 0920, P423 APPELQVIST LA, 1972, RAPESEED, P123 BANFIELD JJ, 1974, 4TH P INT RAP C GIES, P609 BEAREROGERS JL, 1972, LIPIDS, V7, P46 BEAREROGERS JL, 1977, PROG CHEM FATS OTHER, V15, P29 BIANCHI L, 1972, HUM PATHOL, V3, P237 BORG K, 1975, ACTA MED SCAND S, V585, P5 BOROWICZ JW, 1973, ACTA MED POL, V14, P89 CHEN TS, 1977, ESSENTIAL HEPATOLOGY, P1 CHRISTIANSEN RZ, 1979, BIOCHIM BIOPHYS ACTA, V573, P417 CONACHER HBS, 1972, J AM OIL CHEM SOC, V49, P283 DAUN JK, 1977, J AM OIL CHEM SOC, V54, P351 DECRAEMER D, 1994, J LIPID RES, V35, P1241 DOWNEY RK, 1971, J AM OIL CHEM SOC, V48, P718 ENGFELDT B, 1975, ACTA MED SCAND S, V585, P15 FENWICK GR, 1980, ANIM FEED SCI TECHNO, V5, P255 FLAKS B, 1971, J ANAT, V108, P563 GHADIALLY FN, 1988, ULTRASTRUCT PATHOL, P162 GILROY C, 1995, HISTOL HISTOPATHOL, V10, P301 HAEFFNER EW, 1970, LIPID, V5, P430 HULAN HW, 1976, LIPIDS, V11, P9 ISHII H, 1980, BIOCHIM BIOPHYS ACTA, V617, P1 JOHNSON SP, 1977, J FOOD COSMET TOXICO, V15, P348 KRAMER JKG, 1973, J NUTR, V103, P1696 LAZAROW PB, 1994, LIVER BIOL PATHOBIOL, P293 NEAT CE, 1980, BIOCHEM J, V186, P369 REYNOLDS ES, 1963, J CELL BIOL, V17, P208 ROHR HP, 1973, CURR TOP PATHOL, V8, P1 SEGLEN PO, 1992, EXPERIENTIA, V48, P158 SHAHIDI E, 1983, THESIS U GUELPH ONTA SINGH A, 1976, JUN P CAN FED BIOL S, P12 SINGH A, 1978, ACTA ANAT, V102, P232 SINGH A, 1981, PATHOLOGY, V13, P487 SINGH A, 1986, SWINE BIOMEDICAL RES, V1, P77 SOARES JO, 1980, J SUBMICROSC CYTOL, V12, P457 STERNLIEB I, 1979, PROGR LIVER DISEASES, V6, P81 SVENDSEN O, 1974, J ULTRASTRUCT RES, V48, P342 THOMSSON HJ, 1955, J NUTR, V56, P469 VANVELDHOVEN PP, 1992, J BIOL CHEM, V267, P20065 VLES RO, 1975, ROLE FATS HUMAN NUTR, P433 WARD J, 1977, PUB RAPESEED ASS CAN, V45, P37; NR: 41; TC: 2; J9: HISTOL HISTOPATHOL; PG: 7; GA: TT248
Source type: Electronic(1)
Language
- English
Subjects
- Pathology
- piglet liver
- electron microscopy
- Cell Biology
- RAT-LIVER
- LIVER ULTRASTRUCTURE
- diets
- tower rapeseed oil