Jarrell, J., et al. “Alteration of Primate Ovary Surface Epithelium by Exposure to Hexachlorobenzene: A Quantitative Study”. Histology and Histopathology, vol. 6, no. 4, 1991, pp. 525-9, https://scholar2.islandarchives.ca/islandora/object/ir%3Air-batch6-499.

Genre

  • Journal Article
Contributors
Author: Jarrell, J.
Author: Donald, A.
Author: Singh, A.
Author: Villeneuve, D. C.
Author: Sims, David E.
Date Issued
1991
Abstract

Hexachlorobenzene (HCB) is a fungicide and a pollutant of increasing concern in industrialized regions of the world. Reproductive failure is one of the effects of HCB upon mammals. Alteration of cell shape in the ovary surface epithelium (OSE) of Cynomolgus monkeys following oral administration of HCB was observed in this study. At the lowest dose used, 0.1 mg/kg body weight, a dosage that is associated with follicular degeneration, HCB caused quantifiable changes in length-to-width ratios of OSE. Measurement of cell shape by light microscopy offers a reliable indication of OSE changes induced by HCB.

Note

Department of Anatomy and Physiology, Faculty of Veterinary Medicine, University of Prince Edward Island, Charlottetown, Canada.

SPAIN

LR: 20051117; PUBM: Print; JID: 8609357; 0 (Chorionic Gonadotropin); 0 (Environmental Pollutants); 118-74-1 (Hexachlorobenzene); 9002-67-9 (Luteinizing Hormone); 9002-68-0 (Follicle Stimulating Hormone); ppublish

Source type: Electronic(1)

Language

  • English

Subjects

  • Luteinizing Hormone/administration & dosage
  • animals
  • Epithelium/drug effects
  • Environmental Pollutants/toxicity
  • Lipid Metabolism
  • Reproduction/drug effects
  • Hexachlorobenzene/toxicity
  • Follicle Stimulating Hormone/administration & dosage
  • Dose-Response Relationship, Drug
  • Ovary/drug effects/metabolism/pathology
  • Macaca fascicularis
  • Chorionic Gonadotropin/administration & dosage
  • Female
Page range
525-529
Host Title
Histology and Histopathology
Host Abbreviated Title
Histol.Histopathol.
Volume
6
Issue
4
ISSN
0213-3911

Department